Unit Structure

The Skin Culture Lab & Tissue Bank operates through four integrated units:

  1. Administrative, Documentation & Ethical Affairs

Handles all regulatory, ethical, and documentation requirements, including patient consent, donor consent, approvals, traceability, records, quality documentation, and compliance with hospital and legal standards.

  1. Clinical Assessment & Multidisciplinary Decision-Making

Perform pre- and post-implantation assessment of the wound bed, burn grade, patient condition, infection risk, and treatment suitability. The final treatment plan is selected by a three-consultant team: Plastic & Reconstructive Surgery, Intensive Care Burn Unit, and Pathology.

  1. Cell Culture Section

Responsible for processing patient or donor samples, isolating and expanding cells such as but not limited to “keratinocytes, Fibroblasts, Mesenchymal Stem cells (MSCs)”  or derivatives “, Platelet Rich Plasma (PRP), Platelet Rich Fibrin (PRF), Stromal Vascular Fraction (SVF), monitoring culture quality, and preparing cultured cellular products for approved clinical application.

  1. Cell, Graft & Tissue Bank

Responsible for controlled storage, preservation, quarantine, inventory management, and traceability of cultured cells, skin grafts/homograft’s, amniotic tissues, adipose-derived tissues, and other approved biological materials.

Scope of the Unit

The unit provides specialized services for:

  • Acute and chronic burn wounds

  • Deep partial-thickness and full-thickness burns

  • Major burns with limited autologous donor skin

  • Burn wounds requiring temporary biological coverage

  • Keratinocyte-based burn reconstruction

  • Skin homograft/allograft processing and preservation

  • Adipose-derived regenerative medicine pathways

  • PRP and PRF-assisted wound support

  • SVF-related approved clinical or research pathways

  • Exosome-related research and protocol-based applications

  • Post-burn scars, hypertrophic scars, and contractures

  • Reconstructive and functional restoration after burns

Scope of each section

  1. Administrative, Documentation & Ethical Affairs Unit

Responsible for the governance, consent, documentation, ethics, and compliance of the Skin Culture Lab & Tissue Bank.

Scope:

  • Patient and donor consent

  • Ethical approvals

  • Donor eligibility documentation

  • Regulatory and hospital compliance

  • Biosafety and infection-control records

  • Tissue/cell traceability

  • Quality-control documentation

  • Clinical audit and outcome records

  • Research documentation

  1. Clinical Assessment & Multidisciplinary Decision Unit

Responsible for patient evaluation before and after implantation and selection of the most suitable treatment strategy.

Scope:

  • Burn grade and depth assessment

  • Wound-bed evaluation

  • Patient general condition assessment

  • Infection-risk assessment

  • Donor-site availability assessment

  • Pre-implantation planning

  • Post-implantation follow-up

  • Selection of the best treatment option by three consultants:
    Plastic & Reconstructive Surgery, Intensive Care/Burn Unit, and Pathology

  1. Cell Culture Unit

Responsible for cell processing, culture, expansion, and preparation for clinical use.

Scope:

  • Skin biopsy reception

  • Keratinocyte isolation

  • Cell expansion and monitoring

  • Culture quality checks

  • Preparation of cultured epithelial cells

  • Laboratory documentation and traceability

  1. Cell, Graft & Tissue Bank Unit

Responsible for storage, preservation, quarantine, release, and inventory control of biological materials.

Scope:

  • Storage of cultured cells

  • Preservation of skin grafts and homograft’s/allografts

  • Storage of adipose-derived tissues when applicable

  • Quarantine pending safety results

  • Quality release before clinical use

  • Cold chain/cryopreservation monitoring

  • Donor-to-recipient traceability

Eminent Procedures

  1. Autologous Keratinocyte Culture

A small skin biopsy may be taken from the patient and processed in the Skin Culture Laboratory to isolate and expand keratinocytes for later use in burn wound coverage.

  1. Cultured Epithelial Cell Application

Cultured epithelial cells may be applied to selected prepared wounds according to the clinical protocol, wound condition, infection status, and timing of cell availability.

  1. Living-Donor Skin Homograft / Allograft Processing

Redundant excised skin from body-contouring or lipoplasty-related excisional surgery may be donated, processed, preserved, quarantined, and released as temporary biological coverage for selected burn patients.

  1. Adipose-Derived Tissue Processing

Lipoaspirate or adipose tissue obtained during lipoplasty/liposuction may be processed for approved SVF, adipose-derived regenerative, reconstructive applications.

  1. PRP and PRF-Assisted Burn Wound Support

PRP and PRF may be used as adjuncts in selected cases to support wound healing, graft integration, donor-site healing, or scar modulation.

  1. Skin Homograft Coverage for Major Burns

Skin homograft/allograft may be used as temporary biological coverage after excision of extensive burns, especially when the patient’s own donor skin is limited.

  1. Integrated Burn Coverage Pathway

Selected patients may receive a staged plan combining excision, skin homograft, autograft, cultured keratinocytes, amniotic membrane, PRP/PRF, regenerative adjuncts, and rehabilitation.

What We Provide & Treat

We Provide

  • Burn wound stabilization

  • Keratinocyte culture

  • Cultured epithelial cell application

  • Living-donor skin homograft/allograft processing

  • Skin allograft preservation and storage

  • Temporary biological burn coverage

  • Adipose-derived regenerative tissue processing

  • PRP and PRF-assisted wound support

  • SVF-related approved pathways

  • Advanced wound-bed preparation

  • Training and research programs

We Treat

  • Major burns

  • Deep partial-thickness burns

  • Full-thickness burns

  • Burns with limited donor skin

  • Non-healing burn wounds

  • Chronic wounds

  • Failed graft or delayed graft healing

  • Hypertrophic scars

  • Post-burn contractures

  • Functional impairment after burns

  • Complex reconstructive cases.

Head of Department

Nashwa Nagy El-Khazragy

Head of Department

Newsroom

Outcomes


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